Letrozole is a medication that belongs to a class of drugs known as aromatase inhibitors. It is primarily prescribed for the treatment of hormone receptor-positive breast cancer in postmenopausal women. By inhibiting the enzyme aromatase, letrozole reduces the production of estrogen, which plays a crucial role in promoting the growth of certain types of breast tumors.
Estrogen, a female sex hormone, is produced in various tissues of the body including the adrenal glands, fat cells, and ovaries in premenopausal women. In postmenopausal women, estrogen is mainly produced through the conversion of androgens (male hormones) into estrogen by the enzyme aromatase.
In certain cases, breast cancer cells can rely on estrogen for growth and survival. These cancer cells may have hormone receptors on their surface, such as estrogen receptors (ER-positive), which allow them to respond to estrogen stimulation. By blocking the production of estrogen, letrozole deprives these cancer cells of the hormone they need to grow and spread.
Letrozole is typically administered orally in the form of tablets and is taken once daily. It is usually prescribed as part of a comprehensive treatment plan that may include surgery, radiation therapy, or other chemotherapy medications.
It is important to note that letrozole is only effective in treating hormone receptor-positive breast cancer and is not intended for use in hormone receptor-negative or premenopausal individuals. Additionally, it is essential to follow the prescribed dosage and duration of treatment as directed by a healthcare professional, as improper use may lead to adverse effects.
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Letrozole is a medication commonly used in the treatment of breast cancer in postmenopausal women. While it can be purchased from various sources, it is essential to consult with a healthcare professional before buying and using letrozole to ensure its appropriate use and dosage. Taking into account the potential side effects and drug interactions, it is crucial to follow the guidance of a medical expert throughout the buying process and during the course of treatment.